Position:home>News>Contrast induced nephropathy released an expert consensus
Contrast induced nephropathy released an expert consensus
From;  Author:
Recently, the Great Wall in the twentieth meeting of the International Cardiology, "an expert consensus contrast induced nephropathy" (hereinafter referred to as the "consensus") released. Radiation of a number of cardiovascular and renal field experts on the "consensus" Gave insight into the overall content, the experts stressed the cardiovascular doctors and patients who received the intervention contrast nephropathy must pay full attention to the problem. 80s of last century, the international began to contrast induced nephropathy (CIN) of the epidemiological investigation, according to the present report, CIN incidence in different risk groups is very different, less than 1% of the general population However, impaired renal function is about 7-8% of the population, combined with impaired renal function up to 50% of people with diabetes. With the emergence of isotonic contrast agent, clinical comparative study of contrast induced nephropathy has become a hot spot. The last decade, due to the deepening understanding of CIN, the use of risk reduction measures, and iodine contrast agents decreased renal toxicity, CIN incidence rate has decreased from 15% to 7%. However, the dependence of iodine contrast agent Operation increased, CIN is also a growing number of cases. Research shows that in 4622 hospitalized patients, the incidence of renal dysfunction was 7.2%, which is second only to renal hypoperfusion CIN and renal toxicity of drug-induced renal failure The third most common cause, accounting for all cases 11%, CIN 14% mortality. From June 2008 onwards, led by Professor Hu Dayi, from the domestic heart, well-known experts in the field of radiation and the composition of kidney core expert group, in full swing "consensus" of the written work, after discussion, after more than 10 Months, several drafts and reach consensus. The "consensus" during the development of the Chinese Medical Doctor Association of Cardiovascular Medical Association and many national experts in the field of cardiovascular support, clear guidance on high-risk patients isotonic The recommended contrast agent, and provides clinicians with a reasonable strategy for reducing the risk of CIN. "Consensus" made it clear that application of contrast agent before the test, renal function should be evaluated, and thus recommended the estimated glomerular filtration rate, but in emergency surgery, imaging should be carried out as soon as possible, if its benefits can be Can be more than wait, the surgery may be an unknown outcome of serum creatinine or eGFR circumstances. For patients with risk of CIN, a lot of contrast agent can lead to a higher incidence of CIN; and for very high-risk patients, a small amount of Iodine contrast agent can lead to CIN and acute renal dysfunction, suggesting that CIN is no threshold effect occurs. For the same patient if there are multiple risk factors for CIN or high-risk clinical situation, after the application of contrast agent, CIN's Increased risk of extreme, some patients even required dialysis. As a consensus project sponsor, Beijing University People's Hospital, Professor Hu Dayi the "consensus" offered great positive development, he stressed that international consensus and guidance in the production process and the transmission are different. Special Is the guide, most part of high-level senior experts from the final discussion, and then the magazine to be published. And the "consensus" is more focus on its formation process, during which will be finalized through discussions and other interactions To achieve a common participation, joint implementation of the results, and fully mobilize the majority of experts in the field of cardiovascular and doctor's initiative, and then as the "consensus" first step in successful promotion. For treatment of a disease were The unity of knowledge is the expert thinking, and its significance for clinical practice will be far better than the drugs themselves. "Consensus" of development, our primary care doctors for the prevention and treatment in clinical kidney problems contrast agent provided a valuable Evidence and possible options, clinical practice will shorten the gap with clinical treatment guidelines, and promote disease prevention and treatment of CIN in a scientific, standardized and modernized will play a positive role. Eventually reduce the incidence of contrast induced nephropathy, making Fuk the majority of patients.